Dominique Gagliardi & Hélène Zuber, PhD. Group leader at UPR 2357 – IBMP CNRS
![](https://labex-netrna.cnrs.fr/wp-content/uploads/2024/01/Gagliardi-Zuber.jpg)
Contact
Dominique Gagliardi / Hélène Zuber
Phone / Phone
E-Mail / E-Mail
Website / Website
UPR 2357 – IBMP CNRS
Institut de Biologie Moléculaire des Plantes du CNRS
12 rue du Général Zimmer
67084 Strasbourg Cedex
France
Research topics
- RNA degradation in plant genome expression and development
- Non-canonical polyadenylation in non-coding RNA metabolism
- Uridylation in RNA degradation/translation repression
Role in NetRNA
The group of Hélène Zuber and Dominique Gagliardi will contribute to the NetRNA network by providing knowledge on RNA degradation mechanisms. The group will study mechanisms of RNA substrate recognition by the degradation machinery and is especially interested in determining the impact of non-canonical polyadenylation and uridylation in controlling activity and stability of non-coding RNAs. Primary information will be gained using the plant model Arabidopsis thaliana. The program is expected to yield both plant-specific information and knowledge that will be translated in other organisms through NetRNA-internal collaborations.
Working Group
Publications
2023
An extensive survey of phytoviral RNA 3' uridylation identifies extreme variations and virus-specific patterns Article de journal
Dans: Plant Physiol, vol. 193, no. 1, p. 271–290, 2023, ISSN: 1532-2548.
No-go decay as a novel route to restrict viral infection in plants Article de journal
Dans: Mol Plant, 2023, ISSN: 1752-9867.
2022
Catalytic activities, molecular connections, and biological functions of plant RNA exosome complexes Article de journal
Dans: Plant Cell, vol. 34, no. 3, p. 967–988, 2022, ISSN: 1532-298X.
A NYN domain protein directly interacts with DECAPPING1 and is required for phyllotactic pattern Article de journal
Dans: Plant Physiol, vol. 188, no. 2, p. 1174–1188, 2022, ISSN: 1532-2548.
2021
The TUTase URT1 connects decapping activators and prevents the accumulation of excessively deadenylated mRNAs to avoid siRNA biogenesis Article de journal
Dans: Nat Commun, vol. 12, no. 1, p. 1298, 2021, ISBN: 33637717, (2041-1723 (Electronic) 2041-1723 (Linking) Journal Article Research Support, Non-U.S. Gov't).