Roland MARQUET & Jean-Christophe PAILLART, PhD. Group leaders at UPR 9002 – ArN CNRS
Contacts
R. MARQUET / J-C PAILLART
Phone / Phone
E-Mail / E-Mail
Website
UPR 9002 – ARN CNRS
Institut de Biologie Moléculaire et Cellulaire du CNRS
2 allée Konrad Roentgen
67084 Strasbourg Cedex
France
Research topics
- Selection and encapsidation of the genome and viral assembly of
- Retroviruses
- Influenza A viruses
- Coronaviruses
- Innate cellular defenses against viruses
Role in NetRNA
The Marquet/Paillart group will contribute its knowledge and expertise in structure-function relationship studies of viral RNA genomes to the project. The group will analyze the role of the interactions of the packaging signals present in the genome of coronaviruses (including SARS-CoV-2) with the viral N protein on RNA packaging, liquid-liquid phase separation (LLPS) and on the inhibition of the innate immune system by combining in vitro and in cell experiments.